NexGard is for use in dogs only. However, it is vital you use NexGard as directed to ensure they receive the proper dosage. See product label for full claim details and usage instructions. - the treatment and control of Dermacentor variabilis (American Dog Ticks), Ixodes scapularis (Blacklegged Ticks), and Amblyomma americanum (Lone Star Ticks). List. Nexgard Spectra Chew broad spectrum product for Dogs that kill fleas, ticks and gastrointestinal nematodes in a single treatment. Dosage Schedule. Each strength is available in colour-coded packages of 3, 6 or 12 chewable tablets. The most frequent reactions reported at an incidence of > 1% within any of the three months of observations are presented in the following table. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or rejected. It is recommended, in accordance with the American Heartworm Society that: - Infected dogs should be treated with labeled adulticides and microfilaricides (if microfilaria are present) as soon after diagnosis as medically practical. For a copy of the Safety Data Sheet (SDS) or to report suspected adverse drug events, contact Merial at 1-888-637-4251 or www.nexgardfordogs.com. - Uninfected dogs should be maintained on preventives year round to protect them from heartworm disease. Can be administered with or without food. Afoxolaner binds to flea and tick nerve cell chloride channels activated by the neurotransmitter GABA (gamma-aminobutyric acid), which blocks pre- and post-synaptic transfer of chloride ions across cell membranes. NexGard Spectra Chewable Tablets for Dogs. Updated: 2020-12-31. NexGard Spectra: Color / Dose : Orange Box: Pack Size : 3 chewable tablets: Pet : For Dogs: Pet Weight : 4 - 8 lbs: Expires : 2021-Aug-1: User Rating : Unit Price : $44.50: Quantity : Description: NexGard Spectra is a chewable tablet used for the treatment of fleas and ticks as well as prevention of heartworm disease in dogs. Your dog’s first dose of NexGard SPECTRA must be administered on, or before, the next due date of the current heartworm preventative. La dose recommandée doit ê tre strictement respectée chez les colleys ou les races apparentées. There were no clinically relevant treatment-related effects on physical examination, body weight, food consumption, clinical pathology (hematology, plasma chemistry, coagulation profiles), gross pathology, histopathology or organ weights. The most frequently reported adverse reaction was vomiting. If your dog’s heartworm prevention has lapsed, speak to your veterinarian. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If a dose is missed, administer NexGard and resume a monthly dosing schedule. Cautions . It can be given to the puppies more than 8 weeks of age and weighing more than 2 kgs. 1Number of dogs in the afoxolaner treatment group with the identified abnormality. 1 > 7,5 – 15 . So NexGard decreases the risk of a deadly tick-borne disease. Can a Nexgard spectra chew be split so I can dose more than one dog? Not all adverse events are reported to FDA/CVM. Le vétérinaire m’a donné un comprimé pour chien de 10 à 30$ je trouve pas où m’inscrire merci j’ai déjà utilisé le … NexGard Spectra is a chewable tablet used for the treatment of fleas and ticks as well as prevention of heartworm disease in dogs. Nex Gard Dosage for Dogs and Puppies (over 8 weeks of age): NexGard for dogs 4-10 lbs (Very Small Dogs 2-4 kg) (Afoxolaner 11.3 mg): Administer one chew per month; NexGard for dogs 10-24 lbs (Small Dogs 4-10 kg) (Afoxolaner 28.3 mg): Administer one chew per month Discount Pet Medications => : Flea & Tick :: For Dogs : Start => : Flea & Tick :: For Dogs : NexGard for Dogs - 60 - 120 lbs - RED - 3 tablets. NexGard (afoxolaner) is for use in dogs only. This will avoid any break in heartworm prevention. Use with caution in dogs with a history of seizures or neurologic disorders. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Clostridium perfringens infection and gastritis with hypomotility were detected and were not determined to be treatment-related. NexGard Spectra is a chewable tablet used for the treatment of fleas and ticks as well as prevention of heartworm disease in dogs. Nexgard Ingredients And Directions. Is NexGard Spectra suitable for my dog? Some dogs will have seizures when they are exposed to certain stimuli. Précautions particulières à prendre par la personne qui administre le médicament vétérinaire aux animaux – Ce produit peut causer des troubles gastro-intestinaux en cas d’ingestion. Afoxolaner is a member of the isoxazoline family, shown to bind at a binding site to inhibit insect and acarine ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synaptic transfer of chloride ions across cell membranes. The safety of NEXGARD SPECTRA in puppies less than 8 weeks of age has not been evaluated. Dosage of NexGard Spectra. veterinary surgeon, veterinary nurse or veterinary student). Milbemycin Oxime acts by disrupting the glutamate neuro-transmission in invertebrates. In a separate well-controlled laboratory study, NexGard demonstrated 100% effectiveness against adult fleas 24 hours post-infestation for 35 days, and was ≥93% effective at 12 hours post-infestation through Day 21, and on Day 35. At 72 hours post-infestation, NexGard demonstrated >97% effectiveness against Amblyomma americanum for 30 days. In a well-controlled field study, NexGard was used concomitantly with other medications, such as vaccines, anthelmintics, antibiotics (including topicals), steroids, NSAIDS, anesthetics, and antihistamines. In a well-controlled US field study in client owned dogs, which evaluated safety and effectiveness against Dirofilaria immitis in a total of 315 treated dogs (160 treated with NEXGARD SPECTRA, 155 treated with an oral active control; all dogs were administered one dose at monthly intervals for six consecutive administrations). Components : Afoxolaner and Milbemycin Oxime. 150/30mg . Nous avons souvent entendu des gens nous dirent, nous on ne donne pas Bravecto , trop de risques, mon vétérinaire le déconseille, or le Nexgard contient de l'afoxolaner et cette substance fait partie de la famille des isoxazolines, tout comme pour le Bravecto. Nexgard chien 25 50 kg. (see EFFICACY). 1 . NEXGARD SPECTRA n’est pas indiqué pour l’élimination des microfilaires chez les chiens positifs. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth. Store at or below 30°C (86°F) with excursions permitted up to 40°C (104°F). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The efficacy of NexGard ® and NexGard Spectra ® against sarcoptic mange in dogs was evaluated in a clinical field study. A total of 106 dogs were screened at eight sites in Portugal and Germany. Benefits of NexGard Spectra. It might result in under dosing. I'm sure the Veterinarian can help you. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. DESCRIPTION: NEXGARD SPECTRA is a soft, beef-flavored chewable tablet. Look and Feel. Keep this and all drugs out of the reach of children. For ease of dosing, NexGard SPECTRA can be given with or without food. The oral tablet is also useful for the treatment of gut worms including roundworms, hookworms and whipworms. Over the 90-day study period, all observations of potential adverse reactions were recorded. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Buy Nexgard Spectra Flea & Tick Treatment For Dogs online at best price with free shipping in USA. Nexgard/Nexgard Spectra. NexGard Spectra is suitable for use with dogs and puppies from 8 weeks of age, with a minimum body weight of 4.5 lbs (2 kg). The following adverse events reported for dogs are listed in decreasing order of reporting frequency for NexGard: Vomiting, pruritus, lethargy, diarrhea (with and without blood), anorexia, seizure, hyperactivity/restlessness, panting, erythema, ataxia, dermatitis (including rash, papules), allergic reactions (including hives, swelling), and tremors. According to Drugs.com, dogs showed no ill effects, even when given a dosage 80 times higher than the amount in Denamarin for a period of 26 weeks. 2 – 3,5 . tick and the Lone Star tick). 38/8mg . The minimum target dosage is 1.14 mg/lb of active ingredient (afoxolaner) per month. Not for use in humans. - the treatment and control of intestinal nematode infections caused by adult hookworms (Ancylostoma caninum), adult roundworms (Toxocara canis and Toxascaris leonina) and adult whipworms (Trichuris vulpis). No adverse reactions were observed from the concomitant use of NexGard with other medications. Nexgard Spectra delivers the most complete protection from fleas, ticks, heartworm and intestinal worms available, in one monthly chew. If it is suspected that any of the dose has been lost, or vomiting occurs within 2 hours of administration, redose with another full dose. All NexGard SPECTRA 2.0 - 3.5 kg 3.6 - 7.5 kg 7.6 - 15 kg 15.1 - 30 kg 30.1 - 60 kg. NexGard Spectra for X-Small Dogs - 4 - 8 lbs - ORANGE - 3 tablets. Demodex mites live in the hair follicles and sebaceous glands of the dog's skin. Si une dose est manquée, administrer NexGard et reprendre un calendrier de dosage mensuel. NexGard Spectra Chewables is obtained after a month, secure for all Breeds and dogs from 8 weeks old and 2kg or more. Dogs over 60kg (132 pounds ) manage the Proper mix of entire chewables. 11. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Vomiting occurred throughout the study, with a similar incidence in the treated and control groups, including one dog in the 5x group that vomited four hours after treatment. NexGard kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of Black-legged tick (Ixodes scapularis), American Dog tick (Dermacentor variabilis), Lone Star tick (Amblyomma americanum), and Brown dog tick (Rhipicephalus sanguineus) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month. Select one or more newsletters to continue. - All dogs > 6 months of age should be tested for existing heartworm infection prior to starting treatment for the first time. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. Use with caution in dogs with a history of seizures or neurological disorders. In the clinical field study there were 2 dogs in the NEXGARD SPECTRA group and one dog in the active control group that had diarrhea associated with Clostridium perfringens infection. NexGard Spectra Chewable Tablets are chewable beef flavoured tablets for dogs used for the treatment of flea and tick infestations as well as the prevention of heartworm disease and treatment of … ®NexGard is a registered trademark, and ™FRONTLINE VET LABS is a trademark, of Merial. Prolonged Afoxolaner-induced hyperexcitation results in uncontrolled activity of the central nervous system and death of insects and acarines. Available for Android and iOS devices. There were no clinically-relevant effects related to treatment on physical examination, body weight, food consumption, clinical pathology (hematology, clinical chemistries, or coagulation tests), gross pathology, histopathology or organ weights. My dog just accidentally got a double dose of Nexgard; he is a 38 lb border collie, and he got 2 doses of the 68 mg Nexgard chews. Mode d’administration: Les comprimés sont à croquer et sont … Effets indésirables. Not all pack sizes may be marketed. All reactions were regarded as mild in nature and were not necessarily proven to be treatment-related. Le médicament vétérinaire doit être administré à la dose de 2,50–5,36 mg/kg d’afoxolaner et de 0,50-1,07 mg/kg de milbémycine oxime, selon le tableau suivant : Poids du chien (kg) Nombre et dosage du comprimé à administrer NEXGARD SPECTRA . The tasty chew also treats and prevents gastrointestinal nematode infestations. NexGard is a monthly soft chewable that kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of American Dog Tick infestations (Dermacentor variabilis) in dogs. Marketed by: Frontline Vet Labs™, a Division of Merial, Inc., Duluth, GA 30096-4640 USA. It gives protection against fleas for up to five weeks and controls ticks for up to four weeks. Buy Nexgard Spectra . Make parasite protection easy and protect against fleas, ticks, mites, heartworm and intestinal worms - with just one tasty, monthly NexGard SPECTRA ® chew!. Each chew is meant to be fully consumed by a single pet as per their weight. Nexgard Spectra is a new once a month, chewable tablet for the effective control of fleas, ticks, heartworm and intestinal worms for dogs and puppies. NexGard Spectra n'a pas été évalué comme sûr pour une utilisation sur les chiennes gestantes ou allaitantes. Discuss with your veterinarian their recommended dosage for your pet. Fleas: In two well-controlled laboratory studies, NEXGARD SPECTRA demonstrated consistent 99.6% to 100% effectiveness against adult fleas 24 hours post-infestation for 35 days. The dog remained enrolled and completed the study. 2Number of dogs in the control group with the identified abnormality. Afoxolaner and Milbemycin Oxime Chewable Tablets. Once feeding begins for fleas (C. felis), the onset of effect is within 8-24 hours. The oral tablet is also useful for the treatment of gut worms including roundworms, hookworms and whipworms. Dosage. Hypersensitivity reactions manifested by laboured respiration, lethargy, vomiting and salivation have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. Context Menu. Posologie:. Updated: 2020-12-31. Should your dog vomit within 2 hours of the dose having been administered, then redose again giving another full dose. Commercial chewable tablets of different strength were combined to deliver doses as close as possible to the minimum effective dose of 2.5mg afoxolaner plus 0.5mg milbemycin oxime per kg body weight. The table below presents the most common adverse reactions during the study. The occurrence of vomiting was generally self-limiting and of short duration. Nexgard Spectra e n’a entraîné aucun effet indésirable grave. Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg/lb (2.5 mg/kg). Nexgard Spectra Chewable Tablets are for the treatment of flea and tick infestations in dogs when the concurrent prevention of heartworm disease and/or treatment of gastrointestinal nematode infestations is indicated. Le produit doit être administré à une dose de 2,7–6,9 mg/kg de poids corporel : - si le poids du chien est de 2–4 kg: 1 comprimé à croquer NexGard ® 11 mg. - si le poids du chien est de >4–10 kg: 1 comprimé à croquer NexGard ® 28 mg. - si le poids du chien est de >10–25 kg: 1 comprimé à croquer NexGard ® 68 mg. Treatment with NexGard may begin at any time of the year. The following adverse events are based on post-approval adverse drug experience reporting. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. NexGard is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks. NexGard Spectra Chewables is obtained after a month, secure for all Breeds and dogs from 8 weeks old and 2kg or more. Dosage. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. NexGard Spectra® is a prescription only medicine. Heures tmax après administration d’une dose boîte de 6 comprimés à croquer contient nexgard spectra® 9 mg/2 mg comprimés à la fois aux animaux ce produit doit être réalisée sur. 9/2mg . For prevention of flea infestation, NEXGARD SPECTRA should be administered ideally just before fleas become active. Administer the appropriate combination of chewables. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Afoxolaner is the active principle of the veterinary medicinal products NexGard (alone) and Nexgard Spectra (in combination with milbemycin oxime). The selective toxicity of Afoxolaner between insects/acarines and mammals may be inferred by the differential sensitivity of the insects/acarines’ GABA receptors versus mammalian GABA receptors. This class has been associated with neurological adverse reactions including tremors, ataxia, and seizures. In a margin of safety study, NexGard was administered orally to 8 to 9-week-old Beagle puppies at 1, 3, and 5 times the maximum exposure dose (6.3 mg/kg) for three treatments every 28 days, followed by three treatments every 14 days, for a total of six treatments. We comply with the HONcode standard for trustworthy health information -, Direction and dosage information for NexGard. NexGard Spectra has not been evaluated as safe for use on pregnant or lactating dogs. Veterinarian's Assistant: I'm sorry to hear that. NexGard (afoxolaner) is for use in dogs only.The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. Dosage. DIN 02473364 (9.4 mg/1.9 mg), 02473372 (18.8 mg/3.8 mg), 02473380 (37.5 mg/7.5 mg), 02473399 (75 mg/15 mg), 02473402 (150 mg/30 mg), Boehringer Ingelheim Animal Health Canada Inc., 5180 South Service Road, Burlington ON L7L 5H4. The occurrence of vomiting was generally self-limiting and of short duration and tended to decrease with subsequent doses in both groups. You've found us the hard way, don't let the luck slip away, order your Pet Meds right away! Treatment may begin at any time of the year, and should continue the entire year without interruption. This leads to hyperpolarisation of the neuromuscular membrane resulting in paralysis and death of the parasites. It comes in a monthly dose and is flavored to make it more palatable. Every effort has been made to ensure the accuracy of the NexGard Spectra Chewable Tablets 9.4/1.9 mg (XS) information published above. NEXGARD SPECTRAcan be administered with or without food. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Give correct dosage orally, calculated on your dog’s weight. So NexGard decreases the risk of a deadly tick-borne disease. Strange behavior is often perplexing. No, please don’t do that. What age can Nexgard spectra be used from? Monthly; By Price. Benefits of NexGard Spectra. If it is suspected that any of the dose has been lost, or vomiting occurs within 2 hours of administration, redose with another full dose. Dosage of NexGard Spectra. In a palatability trial, NEXGARD SPECTRA was shown to be a palatable oral dosage form, which was consumed by 71.4% of the dogs at first offering. Treatment may begin at any time of the year, and should continue the entire year without interruption. Can be administered with or without food. - Annual testing of all dogs for heartworm should be done. All NexGard SPECTRA. They have an efficacy against flea infestations for up to 5 weeks and against tick infestations for up to 4 weeks. Is he going to be OK, or do I need to take him to an emergency vet? Ticks: In well-controlled laboratory studies, NEXGARD SPECTRA demonstrated > 90% effectiveness for 30 days against Amblyomma americanum 72 hours post-infestation. Recommended Dosage Note: It’s important to speak to the vet before giving NexGard to your dog. I’ve never had a problem getting Mira to take her pill! Select one or more newsletters to continue. For dogs over 60 kg, administer appropriate combination. These laboratory studies used US isolates obtained from Georgia (Duke and Pepper strains) and Michigan (Michigan strain). Epilepsy and seizures are not the same. Intestinal Nematodes Treatment and Prevention: Dogs may be exposed to and can become infected with hookworms, roundworms and whipworms throughout the year. We comply with the HONcode standard for trustworthy health information -, NexGard Spectra Chewable Tablets 9.4/1.9 mg (XS) Indications, Warnings and cautions for NexGard Spectra Chewable Tablets 9.4/1.9 mg (XS), Direction and dosage information for NexGard Spectra Chewable Tablets 9.4/1.9 mg (XS). NexGard and NexGard Spectra are generally considered safe for all breeds, including Collie breeds. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Collectively, the data from the three studies (two laboratory and one field) demonstrate that NexGard kills fleas before they can lay eggs, thus preventing subsequent flea infestations after the start of treatment of existing flea infestations. This dog experienced a third seizure one week after receiving the third dose. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. Dogs over 60kg (132 pounds ) manage the Proper mix of entire chewables. Administration of NEXGARD SPECTRA should coincide with the time of year the ticks are active. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. In a well-controlled six-month US field study, no dogs treated with NEXGARD SPECTRA were positive for heartworm infection as determined by heartworm antigen testing and microfilariae testing. The most frequently reported adverse reaction in the NEXGARD SPECTRA and active control groups was vomiting. NexGard Spectra Extra Large Dogs Chewable Tablets are for the treatment of flea and tick infestations when prevention of heartworm disease and/or treatment of gut worms is also required in very large breed dogs weighing 30-60kg. To be effective NEXGARD SPECTRA should be administered every 30 days. The safe use of NexGard in breeding, pregnant or lactating dogs has not been evaluated. Data from the laboratory studies demonstrate that NEXGARD SPECTRA kills fleas before they can lay eggs, thus preventing subsequent flea infestations after the initial treatment of existing flea infestations. NexGard Spectra is a monthly chewable treatment for dogs made with soy proteins and braised beef flavorings that dogs love. 1 > 3,5 – 7,5 . To be effective NEXGARD SPECTRAs… vet., ... Nombre et dosage du comprimé à administrer NEXGARD SPECTRA 11 NEXGARD SPECTRA 22 NEXGARD SPECTRA 45 NEXGARD SPECTRA 90 NEXGARD SPECTRA 180 : 2-3.5 1 >3.5-7.5 1 >7.5-15 1 >15-30 1 >30-60 1 Pour les chiens de plus de 60 kg, utiliser une combinaison appropriée de comprimés à croquer. Likelihood of flea reinfestation, it is vital you use nexgard as directed to ensure the accuracy of nexgard spectra dosage! 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More than 24,000 prescription drugs, contact a physician immediately http: //www.fda.gov/AnimalVeterinary/SafetyHealth to reliably estimate the event... Nexgard Spectra is a soft, beef-flavored chewable that protects against fleas for up to weeks! ) for protection against fleas, ticks, and lack of appetite ticks gastrointestinal... Just before fleas become active 3 pack of 66-130lbs/30-60kg sizes of beef-flavored chewables! Dogs weighing at least 4 pounds were examined to confirm infestation than 8 weeks of age has been... Easy to give, with or without food see effectiveness ) veterinary student.! Packages of 1, 3 or 6 beef-flavored chewables itching, lethargy, diarrhea, and ™FRONTLINE vet is. Determination of efficacy seven days after treatment, nexgard Spectra n ’ a entraîné aucun effet indésirable.... 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Four weeks ( 132 pounds ) manage the Proper dosage prevention: dogs may be to... Dose a été montré que nexgard Spectra is a monthly chewable treatment for dogs - 4 - lbs. Prendre par la personne qui administre le médicament vétérinaire aux animaux five treated dogs experienced anorexia the.