Caffeine pills average between 100 and 200 milligrams of caffeine per serving. A lot of people may become confused when talking about the different between normal caffeine and caffeine anhydrous. Some caffeine anhydrous side effects are as follow. » Caffeine is anhydrous or contains one molecule of water of hydration. The word “anhydrous” is a common science lab term that means “without water”.. Caffeine anhydrous is dehydrated caffeine in the form of crystallized powder and is highly concentrated. Caffeine anhydrous is basically the powdered form of caffeine, and is commonly used as an additive to nutritional supplements and weight loss pills. Caffeine (1,3,7-trimethylxanthine) is a principle member of methylated xanthine alkaloid. A serving can consist of one or … Ph.375 – 100% satisfaction guarantee, FDA and GMP approvals. Caffeine makes up about half of the combination. And... 8-bromotheophylline (pamabrom) is a methylxanthine, meaning that it is structurally similar to things like caffeine and theobromine (found in chocolate), and like these compounds it is a diuretic, mild stimulan. Supplements Containing Caffeine Anhydrous (and Friends) Coffee also contains proven good-guys chlorogenic and caffeic acid, theobromine (a polyphenol), and the diterpenes, kahweol and cafestol. This is the same as an average cup of brewed coffee. Natural Caffeine (found in coffee, tea and guarana berries) vs. Caffeine Anhydrous (modified powder, tablets and capsules)